Description

Escaline Also known as:

• 2-(4-Ethoxy-3,5-dimethoxyphenyl)ethanamin[German][ACD/IUPAC Name]

• 2-(4-Ethoxy-3,5-dimethoxyphenyl)ethanamine[ACD/IUPAC Name]

• 2-(4-Éthoxy-3,5-diméthoxyphényl)éthanamine[French][ACD/IUPAC Name]

• 3,5-Dimethoxy-4 ethoxyphenylethylamine

• 39201-82-6[RN]

• Benzeneethanamine, 4-ethoxy-3,5-dimethoxy-[ACD/Index Name]

• Escaline[Wiki]

• Q13F1C1N8I

• 2-(4-ETHOXY-3,5-DIMETHOXYPHENYL)ETHAN-1-AMINE

• 2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine

• Ethylamine, 3,5-dimethoxy-4-ethoxyphenyl-

• MFCD01727071

• UNII:Q13F1C1N8I

First synthesised in the 50s, this uncommon drug was reexamined by David Nichols in the 1990s. It is an analogue of mescaline which is roughly six times more potent, and is thus a powerful psychedelic phenethylamine. Subjective effects may include stimulation and hallucinations.

Summary

It is a closely related structural analog of mescaline with which it shares many common properties. Escaline was first synthesized and reported in the scientific literature by Benington, et al. , in 1954, but was later re-examined in the laboratory of David E.

Nichols who prepared a series of mescaline analogues, including proscaline, jimscaline, isoproscaline, and others. The effects of escaline were first described by Alexander Shulgin in his book PiHKAL: A Chemical Love Story. He lists the dosage range as 40 mg to 60 mg orally and describes the duration of action to be 8–12 hours.

Shulgin states that escaline “differs from mescaline in that the onset of action is quicker (within the first hour) and there is no nausea noted, but otherwise the time course, and much of the qualitative content, is quite similar. ”

Chemistry

Escaline contains two methoxy functional groups CH3O- which are attached to carbons R3 and R5 as well as an additional ethoxy group at carbon R4 of the phenyl ring.

Escaline is the 4-ethoxy analog of mescaline.

Dose Chart

Duration Chart

Legal Status

Sources