Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.
Psychedelics are substances (natural or laboratory made) which cause profound changes in a one’s perceptions of reality. While under the influence of hallucinogens, users might hallcuniate visually and auditorily.
Disclaimer: Psychedelic drugs offer some of the most powerful and intense psychological experiences. Additionally these substances are illegal in many places. We understand that even though these substances are illegal, their use occurs frequently. We do not condone breaking of the law. By providing accurate information about these substances, we encourage the user to make responsible decisions and practice harm reduction.
Description
DOB Also known as:
- 2,5-Dimethoxy-4-bro
moamphetamine [Wiki]
- (±)-1-(4-Bromo-2,5-
dimethoxyphenyl)-2- aminopropane
- (±)-1-(4-Bromo-2,5-
dimethoxyphenyl)-2- aminopropane
- (±)-2,5-Dimethoxy-4
-bromoamphetamine
- (±)-2,5-Dimethoxy-4
-bromoamphetamine
- (±)-4-Bromo-2,5-dim
ethoxy-α-methylphen ethylamine
- 1-(4-Brom-2,5-dimet
hoxyphenyl)-2-propa [German][ACD/IUPAC Name]namin
- 1-(4-Bromo-2,5-dime
thoxyphenyl)-2-prop [ACD/IUPAC Name]anamine
- 1-(4-Bromo-2,5-dimé
thoxyphényl)-2-prop [French][ACD/IUPAC Name]anamine
- 1-(4-Bromo-2,5-dime
thoxyphenyl)propan- 2-amine
- 4-Bromo-2,5-dimetho
xy-amphetamine
- 5874
- 64638-07-9[RN]
- Benzeneethanamine,
4-bromo-2,5-dimetho [ACD/Index Name]xy-α-methyl-
- Benzeneethanamine,
4-bromo-2,5-dimetho xy-α-methyl-, (±)-
- brolamfetamine[INN]
- brolamfétamine[French][INN]
- BROLAMFETAMINE, (R)-
- BROLAMFETAMINE, (S)-
- Brolamfetaminum[Latin][INN]
- brolamphetamine
- brolanfetamina[Spanish][INN]
- dl-2,5-Dimethoxy-4-
bromoamphetamine
- броламфетамин[Russian][INN]
- برولامفيتامين[Arabic][INN]
- 布苯丙胺[Chinese][INN]
- (±)2-(4-Bromo-2,5-d
imethoxy-phenyl)-1- methyl-ethylamine
- (±)-2,5-Dimethoxy-4
-bromoamphetamine
- (±)-4-Bromo-2,5-dim
ethoxy-α-methylphen ethylamine
- [3
H](+)DOB
- 1-(4-bromo-2,5-dime
thoxyphenyl)-2-amin opropane
- 2-(2-Methoxy-Phenyl
)-1-Methyl-Ethylami ne
- 2-(4-Bromo-2,5-dime
thoxy-phenyl)-1-met hyl-ethylamine
- 2-(5-Bromo-2,4-dime
thoxy-phenyl)-1-met hyl-ethylamine
- 2,5-dimethoxy-(4-br
omo)phenylisopropyl amine
- 2,5-DIMETHOXY-4-BRO
MAMPHETAMIN
- 2,5-DIMETHOXY-4-BRO
MAMPHETAMINE
- 2,5-dimethoxy-4-bro
moamphetamine|DOB
- 2,5-DIMETHOXY-4-BRO
MOAMPHETAMINE-D6
- 32156-26-6[RN]
- 43061-15-0[RN]
- 43061-16-1[RN]
- 4-Bromo-2,5-dimetho
xy-a-methylbenzenee thanamine
- 4-Bromo-2,5-dimetho
xyamphetamine
- 4-bromo-2,5-dimetho
xyphenylisopropylam ine
- 4-bromo-2,5-dimetho
xyphenylisopropylam inerolamfetamine
- 4-bromo-2,5-dimetho
xy-α-methylbenzenee thanamine
- 4-Bromo-DMA
- Benzeneethanamine,4
-bromo-2,5-dimethox y-α-methyl-(±)-
- DOB
- DOB-4
DOB is a relatively uncommon synthetic psychedelic. It is best known for its very low doses and long duration. Historically it has rarely been taken deliberately, but in place of LSD, however it has recently found its own place in the research chemical scene.
Summary
It is a member of the DOx family of psychedelic amphetamines. While DOB had first been synthesized in 1967 and briefly tested in 1971, it took until the 1991 publication of the book PiHKAL ("Phenethylamines I Have Known And Loved") by Alexander Shulgin to be documented in-depth. Today, DOB is used as a recreational drug and an entheogen.
It is still rarely sold online but is more commonly found in the streets the form of misrepresented LSD due to its ability to fit onto similar-sized blotter paper. Very little data exists about the pharmacological properties, metabolism, and toxicity of DOB in humans. Along with its sensitive dose-response, unusually long and unpredictable duration, many reports also suggest that this substance may be overly difficult to use safely for those who are not already very experienced with using hallucinogens.
It is highly advised to use harm reduction practices if using this substance.
Chemistry
Amphetamines are substituted phenethylamines containing a phenyl ring bound to an amino (NH2) group through an ethyl chain and a methyl group bound to the alpha carbon Rα.
DOB contains methoxy functional groups OCH3 attached to carbons R2 and R5 as well as a bromine atom attached to carbon R4 of the phenyl ring.
DOB is the amphetamine analogue of the phenethylamine 2C-B.
Common Name | 2,5-Dimethoxy-4-bromoamphetamine |
Systematic name | 2,5-Dimethoxy-4-bromoamphetami |
Formula | C_{11}H_{16}BrNO_{2} |
SMILES | CC(Cc1cc(c(cc1OC)Br)OC)N |
Std. InChi | InChI=1S/C7H6O4/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,8-9H,(H,10,11) |
Std. InChiKey | UIAFKZKHHVMJGS-UHFFFAOYSA-N |
Avg. Mass | 274.1542 Da |
Molecular Weight | 274.1542 |
Monoisotopic Mass | 273.036438 Da |
Nominal Mass | 273 |
ChemSpider ID | 55902 |
Become an Exclusive Member For Free
Become a member now, sign up, and get free updates, news articles, and the latest happenings in the Psychedelic World.
Dose Chart
Oral | |
---|---|
Threshold | 500ug |
Light | 750ug |
Common | 750-1100ug |
Heavy | 1100-1500ug |
Dangerous | 3000ug |
Duration Chart
DOB Duration Data | |
---|---|
Onset | 30-120 minutes |
Duration | 8-24 hours |
After-effects | 2-12 hours |
Interactions
Caution
- Mescaline
- NBOMes
- 2C-x
- 2C-T-x
- 5-MeO-xxT
- The 5-MeO class of tryptamines can be unpredictable in their interactions, particularly increasing the risk of unpleasant physical side effects.
- Cannabis
- Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.
- MXE
- As an NMDA antagonist MXE potentiates DOx which can be unpleasantly intense
- MDMA
- The combined stimulating effects of the two can be uncomfortable. Coming down on the MDMA while the DOx is still active can be quite anxiogenic.
- Caffeine
- High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating it may cause some physical discomfort.
- MAOIs
- MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably
Dangerous
- DXM
- The DOx class as psychedelic stimulants have the potential to mask the effects of DXM and could lead to redosing to an unsafe level. DXM can also potentiate DOx resulting in an unpleasantly intense experience.
- PCP
- Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.
- Amphetamines
- The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of amphetamine can easily lead to thought loops. Coming down from amphetamines while the DOx is still active can be quite anxiogenic.
- Cocaine
- The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of cocaine can easily lead to thought loops. Coming down from cocaine while the DOx is still active can be quite anxiogenic
- Tramadol
- Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.
Low Synergy
- Alcohol
- Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk.
- GHB/GBL
- Benzodiazepines
- SSRIs
No Synergy
- Opioids
- No unexpected interactions.
High Synergy
- Mushrooms
- LSD
- DMT
- Ketamine
- Ketamine and psychedelics tend to potentiate each other - go slowly.
- N2O
Legal Status
Internationally, DOB is a Schedule I drug under the Convention on Psychotropic Substances.
Sources
References
- Shulgin, A., & Shulgin, A. (1991). Erowid Online Books: "PIHKAL" - #62 DOB. Retrieved April 14, 2017.
- http://isomerdesign.com/PiHKAL/read.php?domain=pk&id=62
- http://www.erowid.org/library/books_online/pihkal/pihkal062.shtml
- DOB and Other Possible Prodrugs | http://www.cognitiveliberty.org/shulgin/blg/2005/05/dob-and-other-possible-prodrugs.html
- Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. https://doi.org/10.1007/BF03161089
- http://web.archive.org/web/20070302130637/http://www.incb.org/pdf/e/list/green.pdf
- http://isomerdesign.com/Cdsa/schedule.php?schedule=3§ion=1&structure=C
- "Erste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften" (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
- "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
- "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
- Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086
- http://isap.sejm.gov.pl/DetailsServlet?id=WDU20111050614 2011$06$08&min=1
- http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html
Resources
-
1717 CheMall OR025133
-
1717 CheMall OR182126
-
A&J Pharmtech AJ-154472
-
A&J Pharmtech AJ-20676
-
abcr AB115961
-
ABI Chemicals AC1Q1GY2
-
AChemo
-
AK Scientific 568764
-
AK Scientific D764
-
AKos AKOS001434143
-
Alfa Aesar A13545
-
Alfa Chemistry ACM89861
-
Alichem A015037797
-
ALK ALG00006256
-
Amadis Chemical A843354
-
Ambeed A105508
-
American Custom Chemicals Corp CHM0019547
-
Angene AG-K-79733
-
Angene AGN-PC-0JK5VS
-
Anward ANW-39377
-
AOKBIO AB4272
-
AOKChem AB4272
-
Apollo Scientific Limited OR4893
-
Ark Pharm, Inc. AK-88714
-
Aromsyn AS00962
-
Atomax jiji07455
-
Aurora Fine Chemicals A00.537.738
-
Aurora Fine Chemicals K02.108.063
-
BePharm 2,4-Dihydroxybenzoic acid
-
BePharm B23045
-
BGS International BG00600767
-
BGS International BG01499734
-
BGS International BG04454642
-
Bide Pharmatech BD23045
-
BindingDB 74208
-
BIONET-Key Organics DS-18507
-
Biosynth W-100355
-
Biosynth Carbosynth FD34721
-
BLDpharm BD23045
-
BOC Sciences 89-86-1
-
Cambridge Chem B23045
-
Cambridge Chem CC23063
-
Cambridge Structural Database CCDC reference 245900
-
Cambridge Structural Database CCDC reference 245901
-
Cambridge Structural Database CCDC reference 245902
-
Cambridge Structural Database CCDC reference 245903
-
Cambridge Structural Database CCDC reference 747943
-
Cambridge Structural Database CCDC reference 747944
-
Cambridge Structural Database CCDC reference 747945
-
Cambridge Structural Database CCDC reference 820616
-
CambridgeSoft Corporation 8357
-
ChemAdvisor OHS69010
-
ChemAdvisor OHS69010
-
ChEMBL CHEMBL328910
-
Chembo Pharma KB-17590
-
ChemDB 3964728
-
ChemDB 6139974
-
ChemDB 7123144
-
Chemenu CM157314
-
ChemIDplus 000089861
-
ChemIDplus 001125582
-
ChemIDplus 017289702
-
ChemIDplus 020936327
-
ChemIDplus 020936338
-
ChemIDplus 032628050
-
ChemIDplus 041453503
-
ChemIDplus 154903374
-
ChemIDplus 89861
-
ChemScene 89-86-1
-
Chemspace CSC000212172
-
ChemSynthesis 14509
-
Collaborative Drug Discovery 948137
-
Crystallography Open Database (COD) 4500158
-
CSDeposition Service DB02839
-
DiscoveryGate 1491
-
DiscoveryGate 183143
-
DiscoveryGate 205066
-
DiscoveryGate 328147
-
DiscoveryGate 62915
-
DrugBank DB02839
-
DTP/NCI 13564
-
DTP/NCI 169726
-
DTP/NCI 305801
-
DTP/NCI 4740
-
Egon Willighagen
-
eMolecules 502528
-
Enamine EN300-06121
-
eNovation Chemicals D409457
-
EPA DSSTox 229_NTPBSI_v2b
-
EPA DSSTox DTXCID205074
-
FDA UNII - NLM LU39SC9JYL
-
FDA UNII - NLM UNII: LU39SC9JYL
-
Finetech Industry FT-0614326
-
Fluorochem 209146
-
Food and Agriculture Organization of the United Nations 2,4-Dihydroxybenzoic acid
-
Food and Agriculture Organization of the United Nations 4099
-
FooDB FDB000842
-
Glentham Life Sciences GK3564
-
Human Metabolome Database HMDB0029666
-
Human Metabolome Database HMDB29666
-
iChemical EBD2224190
-
Infotherm 12805
-
J&K Scientific 580184
-
Jalor-Chem I01-1418
-
Jean-Claude Bradley Open Melting Point Dataset 14018
-
Jean-Claude Bradley Open Melting Point Dataset 16980
-
Journal of Heterocyclic Chemistry 19850529_X03
-
King Scientific KSC0004TS
-
King Scientific KSC448I6H
-
LabNetwork LN00225288
-
Laboratory Chemical Safety Summary 1491
-
Labseeker SC-25753
-
LeadScope LS-1901
-
Letopharm LT0323863
-
Life Chemicals F1995-0247
-
MassBank JP007230
-
Mcule MCULE-8411449236
-
Merck Millipore 1952
-
Merck Millipore 800738
-
MMDB 1855.3
-
MMDB 50772
-
MMDB 55943
-
MMDB 55944
-
MMDB 785.3
-
MMDB 786.3
-
Molport MolPort-001-641-037
-
MP Biomedicals 207652
-
MuseChem R070480
-
NIAID 018062
-
NIST Chemistry WebBook 3282258011
-
NIST Spectra mainlib_162412
-
NIST Spectra nist ri
-
NIST Spectra replib_229676
-
NIST Spectra replib_287111
-
NIST Spectra replib_5192
-
NMRShiftDB 20035560
-
ONSChallenge ONS-mp:2,4-dihydroxybenzoic_acid
-
Otava Chemicals 2829700
-
Otava Chemicals 2829700.0
-
Otava Chemicals 7993
-
OXchem
-
OXchem AX8023045
-
Paragos 500011
-
Parchem – fine & specialty chemicals 38757
-
Parchem – fine & specialty chemicals 7137
-
PDB DOB
-
Phenol-Explorer 431
-
Phion 21011472
-
PubChem 1491
-
PubMed 1107218
-
PubMed 11235874
-
PubMed 11324622
-
PubMed 11393710
-
PubMed 11453777
-
PubMed 11572595
-
PubMed 11600045
-
PubMed 13159453
-
PubMed 1416914
-
PubMed 15216516
-
PubMed 15264898
-
PubMed 15779927
-
PubMed 15907696
-
PubMed 16482528
-
PubMed 17061836
-
PubMed 1736291
-
PubMed 17374941
-
PubMed 17381146
-
PubMed 1794414
-
PubMed 2385090
-
PubMed 2826422
-
PubMed 2827066
-
PubMed 2931335
-
PubMed 3085219
-
PubMed 4027959
-
PubMed 446414
-
PubMed 5250038
-
PubMed 6182571
-
PubMed 9827415
-
R&D Chemicals 6047
-
Rosewachem RW063060
-
Royal Society of Chemistry b506784g
-
Royal Society of Chemistry b703292g
-
Royal Society of Chemistry B814440K
-
Royal Society of Chemistry b904748d
-
Royal Society of Chemistry c000473a
-
Royal Society of Chemistry DOI 10.1039/b9nj00353c (CCDC reference 747945)
-
Ryan Scientific 047-73375
-
Santa Cruz Biotechnology sc-238335
-
Serum Metabolome Database HMDB0029666
-
Shanghai Race Chemical RV508210066
-
Sigma-Aldrich ALDRICH-D109401
-
Sigma-Aldrich ALDRICH-W379808
-
Sigma-Aldrich D109401
-
Sigma-Aldrich V900767
-
Sigma-Aldrich VETEC-V900767
-
Sigma-Aldrich W379808
-
Specs AE-562/41921969
-
Springer Nature Oxidative Properties of Quinolinium Dichromate
-
Springer Nature Separation and Determination of Phenolcarboxylic Acids by Capillary Zone Electrophoresis with Dynamic Preconcentration on Hypercrosslinked Polystyrene
-
SynQuest 2629-1-26
-
TCI D0568
-
The Merck Index Online cs000000015991
-
Thieme Chemistry 10.1055/s-0034-1378684
-
Thomson Pharma 00018863
-
Thomson Pharma 00077822
-
Tractus Company Limited TR-032903
-
Tractus Company Limited TRA0094558
-
Urine Metabolome Database HMDB0029666
-
Vitas-M STK299216
-
VulcanChem VC293361
-
Wikidata Q209206
-
Wikipedia 2,4-Dihydroxybenzoic acid
-
Wikipedia 2,4-Dihydroxybenzoic_acid
-
Wonderchem WD04C3Q
-
ZINC ZINC00388544
-
zjartschem ZCF08538
Information made possible with:
- PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
- Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
- PubChem National Center for Bio Informatics
- Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
- Wikipedia
Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.
Data is constantly updated so please check back later to see if there is any more available information on this substance.