Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.
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Description
5-MeO-DiPT Also known as:
- 1H-Indole-3-ethanam
ine, 5-methoxy-N,N- [ACD/Index Name]bis(1-methylethyl)-
- 4021-34-5[RN]
- 5-MeO-DIPT
- 5-methoxy-N,N-diiso
propyltryptamine
- N,N-Diisopropyl-5-m
ethoxytryptamine
- N-Isopropyl-N-[2-(5
-methoxy-1H-indol-3 [German][ACD/IUPAC Name]-yl)ethyl]-2-propan amin
- N-Isopropyl-N-[2-(5
-methoxy-1H-indol-3 [ACD/IUPAC Name]-yl)ethyl]-2-propan amine
- N-Isopropyl-N-[2-(5
-méthoxy-1H-indol-3 [French][ACD/IUPAC Name]-yl)éthyl]-2-propan amine
- N-Isopropyl-N-[2-(5
-methoxy-1H-indol-3 -yl)ethyl]propan-2- amine
- [2-(5-methoxy-1H-in
dol-3-yl)ethyl]bis( propan-2-yl)amine
- '4021-34-5
- 482371[Beilstein]
- 5-?METHOXY-?N,?N-?B
IS(1-?METHYLETHYL)- ?1H-?INDOLE-?3-?ETH ANAMINE
- 5-methoxy DiPT
- 5-Methoxy-3-N,N-dii
sopropylaminoethyli ndole
- 5-methoxy-N,N-bis(1
-methylethyl)-1H-in dole-3-ethanamine
- BR-35049
- diisopropyl-[2-(5-m
ethoxy-1H-indol-3-y l)ethyl]amine
- Diisopropyl-[2-(5-m
ethoxy-1H-indol-3-y l)-ethyl]-amine
- FOXY
- MFCD03840209
- N-(1-methylethyl)-N
-{2-[5-(methyloxy)- 1H-indol-3-yl]ethyl }propan-2-amine
- N,N-Diisopropyl-5-m
ethoxy-tryptamine
- N-[2-(5-methoxy-1H-
indol-3-yl)ethyl]-N -(propan-2-yl)propa n-2-amine
- N-[2-(5-methoxy-1H-
indol-3-yl)ethyl]-N -propan-2-ylpropan- 2-amine
- N-[2-(5-methoxy-1H-
indol-3-yl)ethyl]-N -propan-2-yl-propan -2-amine
- N-{2-[5-(methyloxy)
-1H-indol-3-yl]ethy l}-N-(propan-2-yl)p ropan-2-amine
- N-2-(5-methoxy-1H-i
ndole-3-yl)ethyl-N- [ACD/IUPAC Name](propane-2-yl)propa ne-2-amine
- N-isopropyl-N-(2-(5
-methoxy-1H-indol-3 -yl)ethyl)propan-2- amine
- PDSP1_000761
- PDSP2_000749
- TL8006514
5-methoxy-di isopropyl tryptamine, also known as ‘foxy’, a psychedelic tryptamine related to DMT, which distorts visual and audio perception. Reported to have a heavy body load at high doses, it behaves similarly to other drugs of its class.
Summary
It is related in structure to DiPT and 5-MeO-MiPT. The first human trials of 5-MeO-DiPT were undertaken by Alexander Shulgin in 1975. who would co-author and publish a paper detailing its synthesis and human psychopharmacology in 1981.
A summary of the synthesis and reports of human use is included in Shulgin’s 1997 book TiHKAL (“Tryptamines I Have Known And Loved”). Anecdotal reports characterize the effects of this compound as highly stimulating and mildly entactogenic, lacking in typical psychedelic visual distortions. Many users report strong physical and tactile effects that serve to enhance libido and sexual pleasure.
Many users note an unpleasant body load accompanies higher dosages. Some users also report sound distortion, which is also noted with the related compound, DiPT. Very little is known about the pharmacological properties, metabolism and toxicity of 5-MeO-DiPT.
It is relatively obscure and has a limited history of human use. It has been sold online as a research chemical. It is highly advised to use harm reduction practices if using this substance.
Chemistry
Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain.
5-MeO-DiPT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains two isopropyl chains bound to the terminal amine RN of its tryptamine backbone (DiPT). 5-MeO-DiPT is the N-substituted diisopropyl homolog of 5-MeO-MiPT.
Common Name | 5-MeO-DIPT |
Systematic name | 5-MeO-DIPT |
Formula | C_{17}H_{26}N_{2}O |
SMILES | CC(C)N(CCc1c[nH]c2c1cc(cc2)OC)C(C)C |
Std. InChi | InChI=1S/C17H26N2O/c1-12(2)19(13(3)4)9-8-14-11-18-17-7-6-15(20-5)10-16(14)17/h6-7,10-13,18H,8-9H2,1-5H3 |
Std. InChiKey | DNBPMBJFRRVTSJ-UHFFFAOYSA-N |
Avg. Mass | 274.4011 Da |
Molecular Weight | 274.4011 |
Monoisotopic Mass | 274.204498 Da |
Nominal Mass | 274 |
ChemSpider ID | 133247 |
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Dose Chart
Oral | |
---|---|
Threshold | 3mg |
Light | 5-10mg |
Common | 8-15mg |
Strong | 15-25mg+ |
Duration Chart
5-MeO-DiPT Duration Data | |
---|---|
Onset | 20-40 minutes |
Duration | 4-8 hours |
After-effects | 2-3 hours |
Legal Status
Sources
References
- Shulgin, Alexander. "Pharmacology Lab Notes #1". Lafayette, CA. (1960-1976). p176 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_labbook1_searchable.pdf
- Shulgin, AT; Carter, MF. N,N-diisopropyltryptamine (DIPT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT). Two orally active tryptamine analogs with CNS activity. Commun. Psychopharmacol., 1 Jan 1981, 4 (5), 363–369 | https://www.ncbi.nlm.nih.gov/pubmed/6949674
- https://erowid.org/library/books_online/tihkal/tihkal.shtml
- The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain (ScienceDirect) | http://www.sciencedirect.com/science/article/pii/S0014299906013811 / https://www.ncbi.nlm.nih.gov/pubmed/17223101
- https://www.ncbi.nlm.nih.gov/pubmed/27461536
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- http://www.sfda.gov.cn/WS01/CL0056/130753.html
- "Vierzehnte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften" (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
- "Anlage I BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
- "§ 29 BtMG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
- http://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html#DLM436576
- http://www.notisum.se/rnp/sls/sfs/20040696.pdf
- Misuse of Drugs Act 1971 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I/paragraph/3
- Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e
Resources
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DiscoveryGate 151182
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DrugBank DB01441
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eMolecules 976961
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EPA DSSTox DTXCID60115700
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Erowid 5-MeO-DIPT
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FDA UNII - NLM 12D06G8W8E
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FDA UNII - NLM UNII: 12D06G8W8E
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Springer Nature A model system for prediction of the in vivo metabolism of designer drugs using three-dimensional culture of rat and human hepatocytes
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Springer Nature Colorimetric detection and chromatographic analyses of designer drugs in biological materials: a comprehensive review
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Springer Nature High prevalence of quasi-legal psychoactive substance use among male patients in HIV care in Japan: a cross-sectional study
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Springer Nature Identification and quantitative determination of 5-methoxy-N,N-di-n-propyltryptamine in urine by isotope dilution gas chromatography-mass spectrometry
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Springer Nature Indolealkylamines: Biotransformations and Potential Drugu2013Drug Interactions
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Springer Nature Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats
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The Merck Index Online cs000000012250
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Thoreauchem TH-B04560
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Wikipedia 5-Methoxy-diisopropyltryptamine
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- PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
- Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
- PubChem National Center for Bio Informatics
- Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
- Wikipedia
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