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Description

4-AcO-MET Also known as:

  • 4-Acetoxy-N-methyl-N-ethyltryptamine
  • 1H-Indol-4-ol, 3-[2-(ethylmethylamino)ethyl]-, acetate (ester)[ACD/Index Name]
  • 3-{2-[Ethyl(methyl)amino]ethyl}-1H-indol-4-yl acetate[ACD/IUPAC Name]
  • 3-{2-[Ethyl(methyl)amino]ethyl}-1H-indol-4-yl-acetat[German][ACD/IUPAC Name]
  • 4-ACETOXYETHYLMETHYLTRYPTAMINE
  • 4-Acetoxy-MET
  • Acétate de 3-{2-[éthyl(méthyl)amino]éthyl}-1H-indol-4-yle[French][ACD/IUPAC Name]
  • Metacetin
  • PCJ17NV1P0
  • 3-{2-[Ethyl(methyl)amine]ethyl}-1H-indol-4-yl acetate[ACD/IUPAC Name]
  • UNII:PCJ17NV1P0

A rare psychedelic tryptamine which is thought to be metabolised into 4-HO-MET. Onset and duration, intensity will vary but effect profile is largely the same.

Chemistry

Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain.

4-AcO-MET is substituted at R4 of its indole heterocycle with an acetoxy (AcO) functional group CH3COO−.

It also contains a methyl group and an ethyl chain bound to the terminal amine RN of its tryptamine backbone (MET).

4-AcO-MET is an acetate ester analog of 4-HO-MET and the N-substituted ethyl homolog of 4-AcO-DMT.

Common Name4-Acetoxy-N-methyl-N-ethyltryptamine
Systematic name4-Acetoxy-N-methyl-N-ethyltryptamine
FormulaC_{15}H_{20}N_{2}O_{2}
SMILESCCN(C)CCc1c[nH]c2c1c(ccc2)OC(=O)C
Std. InChiInChI=1S/C15H20N2O2/c1-4-17(3)9-8-12-10-16-13-6-5-7-14(15(12)13)19-11(2)18/h5-7,10,16H,4,8-9H2,1-3H3
Std. InChiKeyOMDKHOOGGJRLLX-UHFFFAOYSA-N
Avg. Mass260.3315 Da
Molecular Weight260.3315
Monoisotopic Mass260.152466 Da
Nominal Mass260
ChemSpider ID26633897

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Dose Chart

Oral
Light12-18mg
Common20-25mg
Heavy25-35+mg

Duration Chart

4-AcO-MET Duration Data
Onset20-40 minutes
Duration4-6 hours
After-effects2-12 hours

Legal Status

  • Germany: 4-AcO-MET is controlled under the NpSG (New Psychoactive Substances Act) as of July 18, 2019. Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.
  • United Kingdom: 4-AcO-MET is a Class A drug in the UK as it is an ester of the drug 4-HO-MET, which is a Class A drug as a result of the tryptamine catch-all clause.
  • United States: 4-AcO-MET is unscheduled in the United States. It may be considered an analogue of psilocin (4-HO-DMT) which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.

    • Sources

    References

    1. Talaie, H.; Panahandeh, R.; Fayaznouri, M. R.; Asadi, Z.; Abdollahi, M. (2009). "Dose-independent occurrence of seizure with tramadol". Journal of Medical Toxicology. 5 (2): 63–67. :10.1007/BF03161089.  1556-9039.
    2. "Verordnung zur Änderung der Anlage des Neue-psychoaktive-Stoffe-Gesetzes und von Anlagen des Betäubungsmittelgesetzes" (PDF) (in German). Bundesanzeiger Verlag. Retrieved December 10, 2019.
    3. "Anlage NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    4. "§ 4 NpSG" (in German). Bundesministerium der Justiz und für Verbraucherschutz. Retrieved December 10, 2019.
    5. Misuse of Drugs Act 1971 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I/paragraph/3
    6. Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e

    Information made possible with:

    1. PsychonautWiki is a community-driven online encyclopedia that aims to document the field of psychonautics in a comprehensive, scientifically-grounded manner.
    2. Erowid is a non-profit educational & harm-reduction resource with 60 thousand pages of online information about psychoactive drugs
    3. PubChem National Center for Bio Informatics
    4. Chemspider is a free chemical structure database providing fast access to over 34 million structures, properties and associated information.
    5. Wikipedia

    Additional APIs were used to construct this information. Thanks to ChemSpider, NCBI, PubChem etc.

    Data is constantly updated so please check back later to see if there is any more available information on this substance.